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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ff5b88397583efb8f99cafd5c6ec22069514f5657c374f6f0614d780cc017ae' 
  AND token = '4hkEpEG78PAkwR964z+hK6WDGZYLYYH8G5mlGdi5QTU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}