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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8b4b3aed824479f2afdb8744eef38efe379d063a5ccccc8b23fb0c70931a444' 
  AND token = 'bIBI6byIkeFfMKwaCNuxqNGJGyj3tqoR+WRlXv0u0qg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}