SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e03c964922d3aa6543b2768a6acab3b4657a62cf64166485323fccce837a1c2' 
  AND token = 'aGS63tuX8lOy+1rUv+5zp/40/5y0SvYm3m9eDq1Il0I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}