SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4118261522dacf5699d3c7d6c1b13833cd592b44167278ecbe36f609f74576b2' 
  AND token = 'ddewo9ljRNGjhoXoHDNyzBpmfHhDj7wX4/rbi/zDawQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}