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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d9d48ae0ddf428a913e6ae27400f9b836c81fd8ca2e960bf3349788c46ffa31' 
  AND token = 'bd3gVrfi9ybPeGvnVFO0KhVWOnOBGwHBdWRM9cxzkSg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}