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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b2fe509d0bbfb10d4e3474977bc721efafc3c8c17c383e48dd477023c8e32bb' 
  AND token = 'v5F4KadWU9FNPdtr+HuSkjvmtxkx4n8g/+iY5tlQRfM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}