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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6593e91a047730220091d9fabbb7645f24b4211f4d9ce334844b74338396e4c' 
  AND token = '+8lOT0nyUXIbo8KSk/e5VtTOnBOQLstfRmUqXgEJRNs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}