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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd279d243ba216f31ffcfc21330dbeb649e0cd7c506c86daf7c8fd0f183488f7f' 
  AND token = 'ZLs8dOv5UYbD0BfTx/Xn9lNVovsyaNCGW/3/VfWufAg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}