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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '222b1a9dd44ddfe0965a906c34c49be8e4ee5b74ccb9bfca2433bec0bb1097be' 
  AND token = 'kH01pGoQ1zCnTR7LcMffqMAxxRoPf4uKFd7mnlmhLwI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}