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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c250f7717dbdd5a73b6da86b10ff21b356aa514a7e8b87a27d83cdda17e575f' 
  AND token = 'JhE/JBWiwTMkc7J9ViDvOJhWGxJy4aUJ9IqoLeWvhnE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}