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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9b644e20a3411cbd860b720d83bf1762827aa30340217764ee880435fa01e1c' 
  AND token = '7bK9I0ShjAqhOpSz/zVwG0z2RcD2nACDqs4ZDHwhDr0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}