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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8af84613de23db5d8380735dbf0a538f27ec3768e4f1d7e9a5690af2c322e3e' 
  AND token = 'W579J1aSlJLQ6E+WSeYKeXxjt4QE2ssmGQjVt7AyMFE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}