SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2f7eb1f355c3d6bb7d156c29e816ba1b5adc3d8d6deb0093fb0403e33bb1c81' 
  AND token = '+Pj/1JTAlS6IRS/h937lLYmaDpin8OhhTQ5krrnYOg0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}