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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e27fe80f4390b9ac99cb7f85a92ac1be82e3884ea26cea42a4013a2bf32de704' 
  AND token = '1XE5YEQhzVp/m852khfoDtGV3h933iHCEsAkjapDa3w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}