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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f1eb43b9aee49d571e254bd29f586b29ab4121abce7f3db751f08efa326aa9d' 
  AND token = '1zQ1g4UUKTj9a6ajgGKSQoUDNRWDlnBILCUDB/O+12Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}