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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '597e24a8a948d5cea2d24355071a5ff3738e56b801a17b0c55cd8da74b86ac62' 
  AND token = 'fZAonToaxIWjRTnw7k10P94lCqNBsKwCYfSLT1PchrA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}