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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3722e4daab35484c8619d1c0c4eb234ea3f444cebdf9826a0946830ce01d6ae' 
  AND token = 'Eei/lRtTIDeZZ7Ggl1BG/aXck4qlyXbC+0p9hRP9svg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}