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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c409cfbeae26b42f0257ba14c0f601efa8e1836478412815096c9640b4e52b2e' 
  AND token = 'xuU7PHFMTR15sQ8LSJimIWhFihB3J7U8aEwt9YWSpZg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}