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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78ba574d664a18c6722fe0bd1815ca43f0e965d6346c5c64e5df54db1287f326' 
  AND token = 'xp/fns62wGWTmtVrcdGDwv786US2RyFD36eYNFLemLk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}