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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be6220be2895d2a7187fa9ede31d104d87dab0ea47f4fbe2355cacd80d6b9502' 
  AND token = 'j7i3zNYAiyNfuBW9PjBJqJe4LaoUt3gvBTr70KWlppk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}