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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bd857d514e9474f8c53298aa0059982399547d2da00d65b570e974b21a84da1' 
  AND token = 'W0JJukQ121xFmuRxchfmYEjsD+QB7DqBFi7V4hfRZoA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}