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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b14a6e45a9ea9706566aa3d7d14d7ed576dbc391a7732c7938fb361c2bf022a' 
  AND token = 'ztFww96grN1Z50xVsJ2JUal1uY6Xr8X6AHuMUMNhJEc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}