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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12d9bf57e456f7cb90012df9b203f830fc3d609e218e5c3b700538f9508ad281' 
  AND token = 'lqEtK7Z8z2rJG25NtO2yILI/4LurVoVwoVEscKRcIZw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}