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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ba89bd1882204670b5d35bee9c119e81dd001a748dfda0c9c53e0fa787c0e345' 
  AND token = '2kx4CvNDYKMkv+uY9wkLrv8Y2wdVr0CC7vUIKc7YUgw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}