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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '433484d0c2bf640670be3c26c3629ab592269b270e04468ad69e9d4e527bfb77' 
  AND token = 'RLksuaZrlMiASQXcQ3GuuZf9+ocYfIztl7dHC0bh7HM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}