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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '523ae421902bf0e0846a055015a889b3886d618b409814bd8ef19103f86332b1' 
  AND token = 'V1HynxsTWF6AohJiGT6CgIdEDQn6wSV8RnJI9nvr+GM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}