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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce155522938066da6ed57d3dded3cf4e824864e4a176381a555b2f3acf6de741' 
  AND token = '+qPjsLY5e6P3KleVBagcmMH8wAnQ5CaDnyGvRtajpF0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}