SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd79d9406bfab3f191e75c3384e68a36e9671cd678025286ce37ad1ef14ddf729' 
  AND token = 'oX0LZPVN7ueM1aGaFAhhcUFcUO6DkFOObyHf5MeJ6xg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}