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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a14564754a83d454f108d9d12e0e576265aa61feccb771c3395484391980c433' 
  AND token = 'hz3UO8g6w9ejt4eFz5yiWMGnB2xvAv3j14zZeUt1cq4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}