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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b0f3cbccdc2fc835f4207e07855e0f32f5e0453bb820125cc2d164b9ce127a8' 
  AND token = 'PjIN840gNSB+SbcyF56E9G/oV76SGMowt48NUeqSfOs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}