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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '765ab04bce33172fe0dd8e6e178f29be00ad0c599930118aa85d6bfc8909be39' 
  AND token = 'LTqx+uRl9ij84Fw1wF0XGN/BBlLVyuBLyUcYVQvcsbk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}