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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a91b542c835a1747cb09fd3c7da34e242a9da7802cbc4a489702006c5e3af8c' 
  AND token = 'YGDdUB5BprtzFeaZljzbEDEGmf4qkjvTmBW/imOBOLQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}