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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1529ec7944d86b5570ae82944fb4f4238c8cbc5bc7b9bb3c9f4770de3ec5c439' 
  AND token = 'jxuGFlt+5PaLg6+AULpvxcHSzBceuLflfAz9nMxND0Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}