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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7921fe3a9fc3699f2baca5158bb369543f7a5a3acbf7bd83af6f1a3cae999232' 
  AND token = 'r1xErmBmSio+ieKFeiu9snO3tXfO1zFfVhLgt3hCfd0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}