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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9558782da156c7067ca4fdcbd7a8064db60b2b242a44f22c0c006f36b30a8fc2' 
  AND token = 'xzEMso/SCW5tAefxIIt0P+GCVu4RDvzOgIRNhAE/wJs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}