SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b80a9eabc12a05f2eb60e08ad93ee5228b7cc072ab12fe044998444b38c3ad55' 
  AND token = 'uBTlBjnf8jzm67ZNp6715l3k5To2S8PYJlM7noKQVMg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}