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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6425a69f33237d6c09e9106b44f942afd3003070392a183082f0ce262ffc8cb8' 
  AND token = 'Q3im0Ldl+XKUtJTOKDJCUM9pWdJMEL40w9Ya13vIiY8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}