SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5829ed11a41fd3a9f778f913c159a7c0da28c988ac8957abffee83d712cfd13' 
  AND token = 'V14xqGNALMuwgzxeY9z9RnWaa3N4xIjk107rOECH5zg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}