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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a120d791d5bd4d23f6b788ef42df5aa93464f2b38c336c1cfbf5695a928a2382' 
  AND token = '+PhNm2gSCeDrKRn8ktZ8xjS21mSPOD5dBnav2tD5uBQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}