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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9dc0451c80889e0b242dda91d8c1c2d1c80435be9af1efaefc49ca8df26ea0c4' 
  AND token = '+duwWW+V5lv7Elqgj7zXMiRtLAXpE1odrvkaJXYKrFg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}