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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ba21cbd1b0761cc0d534475245628054ec197949f15b2a9e83cfb5425ca4891' 
  AND token = 'nFy4WSiFKhLSPkBfV0g591dgIdT5TFNxd/BcdB8/TtI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}