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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e9e99195e83676fbc7814d755f9201fc0a6304149d8e2461556d8deacc6ebbb' 
  AND token = 'BghU8CT9kLXWKI2ezo0ed8SlLzZu6p6vX1M/7xh6jZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}