SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44abe5005dd5a9924a3042c6a32792fa3f9897daec40f65c105b85a3dde77fa7' 
  AND token = 'rRRml9k3T8wgu0Cqnvpwgy9JofiaUTPptzUNb+gDDeE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}