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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e4cc6c3adfc2ab51158426b96d8a11756878de201b39658b99aa8496c226f23' 
  AND token = 'EG5R4joFZ/qd/ls37CGtXspsHNPxCFfu0SW1gaozITU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}