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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8399f1bc6103a03d8d095d533e3c64af2880af8f98344add5f3335f9c589c28d' 
  AND token = 'KR8DMBmEvlkaf81M+qqMbxjgyW151+S72YaO3MChic8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}