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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26b5e678606288701358d9759111dee2b2428a5664acd26845fe1129e9bc324d' 
  AND token = 'dz5ejWHGqy7cznx7ujr0Iet1j7YFTcFFx0IRKIAUMJw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}