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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24e6c6fdf5ae53365b02d8745855f6d9975c28541449c53b9c24590431d8b95a' 
  AND token = 'gldKCjiUE1xK5GmWgIRUmrfa/6hRuY6xGhu63T+hIsA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}