SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18454805308d1d630cbe92fe4234045874044b43cdc6b52db43c14c65b58fdd7' 
  AND token = 'uEOUxFl5D6cMwCsGc8P29sQ3yBY9vj8ObKn8j/JGm7U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}