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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b72b6664cb94b18c2f1a70290b0944109f5a9b445268ebe2e0180e1aa519c45' 
  AND token = 'G0bbeORjDIUTo26IXEpB8p0NJl6XX/vXkCgzZYDHmjc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}