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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52885bea11b88d0e98c0a84586c17ab4565153cd2703035d9b1666a935f76957' 
  AND token = 'AJT4FeSu+f1dh/15uCv8Co8AXWqm+3Q/HmFNpCjnrnc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}